The Baltimore Ravens and Buffalo Bills are set to clash in a highly anticipated Sunday Night Football matchup, a rematch of last season's AFC divisional playoffs. The Bills narrowly edged out the Ravens with a 29-27 victory, thanks to a failed 2-point conversion attempt by Mark Andrews. This season, both teams are co-favorites at +650 to win Super Bowl 60, making this game a must-watch for NFL fans and bettors alike.

Game Overview

• Date & Time: Sunday, September 7, 2025, 8:20 PM ET
• Venue: Highmark Stadium, Orchard Park, NY
• TV: NBC

Betting Odds

• Spread: Bills -1.5
• Total Points: 50.5
• Moneyline: Ravens -120, Bills +100

Expert Picks

• Matt Bowen: Over
• Pamela Maldonado: Over
• Seth Walder: Under
• Liz Loza: Under
• Eric Moody: Over

Player Props

• Josh Allen: Under 231.5 passing yards (-120), Under 1.5 passing touchdowns (-115)
• Derrick Henry: 2+ touchdowns +375
• Mark Andrews: Over 45.5 receiving yards (-110)

Betting Trends

• Baltimore Ravens: 19-5-1 against the spread as an underdog since 2018.
• Buffalo Bills: 11 straight home wins, the second-longest streak in franchise history.

Key Insights

• Josh Allen: Known for his Week 1 prowess, Allen is expected to be a tough matchup for the Ravens. The Bills' defense, bolstered in the offseason, should be at its peak early in the season.
• Lamar Jackson: The 2023 MVP and 2024 runner-up, Jackson will look to lead the Ravens' offense, supported by Derrick Henry in the running game.
• Mark Andrews: After a challenging end to last season, Andrews aims to bounce back with a strong performance, especially with Isaiah Likely out.

Conclusion

This Ravens vs Bills matchup promises to be a thrilling contest with significant implications for the AFC standings. Whether you're a fan or a bettor, this game offers plenty of excitement and opportunities. Stay tuned for the latest updates and expert analysis to make informed betting decisions.